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KMID : 0359320000400020333
Korean Journal of Veterinary Research
2000 Volume.40 No. 2 p.333 ~ p.337
Pathological findings of lymphocystis in cultured flounders

Abstract
This experiment was done to observe the pathological findings of lymphocystis naturally occurred in the cultured flounders in the southern sea of Korea. Anatomical sign of lymphocystis was characterized by the presence of wart-like nodules on the fins, body surface and mouth. Dense clustering of hypertrophic cells originated from fibroblasts was observed in the lesions. Infected hypertrophic cells had a thick hyaline capsule, large vesiculated nucleus with irregular rims and large nucleolus, and large ribbon-shaped basophilic inclusions at the peripheral zone of the cytoplasm. Hexagonal virus particles with the two layers of capsid were scattered throughout the cytoplasm and were absent from the inclusions.
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